The only previous clash between these two sides, back in October at Anfield, saw the visitors win 3-2, inflicting on the Reds their first home European loss in 10 games.
Liverpool have won just one of their last 10 European games on the road, drawing four and losing five.
Seven of the nine goals that Liverpool have conceded have come after half-time in the EL this season.
Liverpool have scored first in four of their five EL games this season, while
Udinese have conceded first in all five of their EL matches.
Liverpool have lost three of their last five games in Europe against Italian sides (W1 D1 L3).
Only two sides have conceded more goals than Udinese in the 2012-13 Europa League (11).
This will be only the third occasion that Udinese have faced an English side in Europe outside of qualifying - they have won the previous two (incl. the 3-2 win over Liverpool in October).
Seven of the last nine goals that Udinese have conceded in the Europa League have come in the final half hour of games.
All seven of Udinese's 2012-13 EL goals have arrived after half-time.
Udinese striker Antonio Di Natale has been caught offside a joint-high 11 times so far.
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